![]() Talk to your doctor or pharmacist if you have any questions or concerns about metformin. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. However, you should limit your alcohol intake due to the risk of lactic acidosis with metformin. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. Alcohol may also affect blood glucose levels in patients with diabetes. You should seek immediate medical attention if you develop potential signs and symptoms of lactic acidosis such as fatigue, weakness, muscle pain, increasing drowsiness, abdominal pain or discomfort, slow or irregular heartbeat, breathing difficulty, chills, and other unusual symptoms. Lactic acidosis is more likely to occur if you have kidney or liver disease, acute or unstable congestive heart failure, or dehydration. Taking metFORMIN with alcohol may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis, which is a buildup of lactic acid in the blood that can occasionally occur during treatment with metformin-containing products. MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge drinking or frequent consumption) should be avoided during treatment. Patients should also be advised to take precautions to avoid hypoglycemia while driving or operating hazardous machinery. Patients should be advised on the potential signs and symptoms of hypoglycemia (e.g., headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, palpitation, and tachycardia), how to treat it, and to contact their doctor if it occurs. MANAGEMENT: Until more information is available, blood glucose should be monitored if antidiabetic agents are used concomitantly with cinnamon. Hypoglycemia was not reported as an adverse effect in these studies. cassia) for three months did not demonstrate significant differences in fasting blood glucose or HbA1c from baseline to three months. ![]() However, in a double-blinded, RCT in people with type 2 diabetes (n=57), compared to placebo, the administration of oral cinnamon 1 g daily (as C. cassia) for 90 days to usual care reduced HbA1c by a statistically significant 0.83% compared to usual care alone, which lowered HbA1c by 0.37%. In addition, an unblinded RCT in patients with poorly controlled type 2 diabetes managed in primary care in the USA (n=109) reported that the addition of oral cinnamon 1 g daily (as C. ![]() In a randomized control trial (RCT) in people with type 2 diabetes (n=60), it was reported that, compared to placebo, daily doses of 1 g, 3 g, or 6 g of oral cinnamon (as Cinnamomum cassia) consumed for 40 days reduced fasting blood glucose levels by 18% to 29%. ![]() Some small studies have reported that cinnamon reduced fasting blood glucose levels and/or glycosylated hemoglobin (HbA1c) in patients with type 2 diabetes, whereas others have not. Cinnamon has been shown in vitro to increase glucose uptake, glycogen synthesis and insulin sensitivity. MONITOR: Coadministration of cinnamon with antidiabetic drugs and/or insulin may have additive blood glucose-lowering effects, which may potentiate the risk of hypoglycemia. These all help contribute to normal energy metabolism and are present at excellent levels.Consumer information for this interaction is not currently available. Other key nutrients in Multi-Guard® Control include vitamins B1, B3 and B6 (present as P5P, the active form of vitamin B6). Magnesium has been included at 300mg per two tablets as this mineral is involved in over 300 metabolic processes in the body and diets based on highly processed foods will provide, at best, borderline levels.Ĭinnamon has been a favourite with herbalists for many years and we have included a full 2000mg of cinnamon bark the same potency of extract used in published studies. ![]() This is considerably more than you will find in many multiple formulas. Cinnamon has proven anti-inflammatory effects, which can help prevent the development of diabetes, but it has other protective effects as well. The trace mineral, chromium, which contributes to the maintenance of normal blood glucose levels, is included at a generous 200µg per two tablets. This product has several distinctive differences from other multiple formulas and is also an excellent all-rounder, with the most important vitamins and minerals presented at potencies that are generally higher than shop-bought multis. ![]()
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